社区 › 基础知识 › 各种靶向药和化疗药物的说明书

ye1860 发表于 2013-3-6 21:44:21

老马兄很好，很好

老马 发表于 2013-3-13 13:39:37

本帖最后由 老马 于 2013-3-13 13:43 编辑

健择（吉西他滨）+顺铂+阿瓦斯汀
Gemzar +Cisplatin + Avastin
http://annonc.oxfordjournals.org/content/21/9/1804.full
Overall survival with cisplatin–gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL)
Patients and methods: Patients (n = 1043) received cisplatin 80 mg/m2 and gemcitabine 1250 mg/m2 for up to six cycles plus bevacizumab 7.5 mg/kg (n = 345), bevacizumab 15 mg/kg (n = 351) or placebo (n = 347) every 3 weeks until progression. Primary end point was progression-free survival (PFS); OS was a secondary end point.
Results: Significant PFS prolongation with bevacizumab compared with placebo was maintained with longer follow-up {hazard ratio (HR) 0.75 (0.64–0.87), P = 0.0003 and 0.85 (0.73–1.00), P = 0.0456} for the 7.5 and 15 mg/kg groups, respectively. Median OS was >13 months in all treatment groups; nevertheless, OS was not significantly increased with bevacizumab for the 7.5 and 15 mg/kg groups, respectively, versus placebo. Most patients (62%) received multiple lines of poststudy treatment. Updated safety results are consistent with those previously reported.

华为网盘附件：
【华为网盘】ava.JPG

tracy1213 发表于 2013-3-25 20:01:11

这个很实用，很好
谢谢

qiuwen321578 发表于 2013-3-30 17:02:58

知识很全,谢谢老马提供

携手共创奇迹 发表于 2013-4-2 22:03:29

论坛里有用信息真多，努力学习中…

谢谢老马，谢谢大家！

amyamyamy 发表于 2013-4-11 22:24:46

hjt525 发表于 2013-5-1 22:55:50

有没有每个肿瘤的用药组合推荐啊？

秋之韵 发表于 2013-5-2 18:28:02

收藏了谢谢老马。

sharonalen 发表于 2013-5-5 15:14:07

此帖必火

xiamiaoyu 发表于 2013-5-31 13:01:22

老马整理的太好了~~感谢啊！

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