刚下了avastin官网的用药指南:
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Patients should continue treatment until disease progression or unacceptable toxicity. 4 ]7 t, |( w. k1 T
1 Metastatic Colorectal Cancer (mCRC) $ ], }# ?0 V/ ^" K
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
3 b9 d. ~6 c5 n- `4 Wintravenous 5-FU-based chemotherapy. - f( E; Y) A5 h0 I
• Administer 5 mg/kg when used in combination with bolus-IFL.
- {2 l: D- F- A( T8 _1 k• Administer 10 mg/kg when used in combination with FOLFOX4.
0 `- f3 _1 h- o; `" ?2 {2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
) k/ q; |3 t# ?& t h The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and 6 Q$ X7 N, F3 y9 M. v) ^
paclitaxel.
2 u' |$ n. D; S" x+ o; Z* L3 Metastatic Breast Cancer (MBC) Y7 f+ T$ a3 ]3 \* c. U
The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel. % {# X1 k7 J9 f. N3 d
4 Glioblastoma
3 a6 `& J g! p( h5 s. T The recommended dose is 10 mg/kg every 2 weeks.
- r, @# W9 ?. I4 v: }" m& j5 Metastatic Renal Cell Carcinoma (mRCC)
8 V5 k, ~& _1 N, | The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. 2 t3 E! S* H+ I- K0 ?
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按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
4 g8 o* Z$ _2 M$ f) |* r9 W5 w我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |